Metabolic Dysfunction and Neurodegeneration: Pharmacological Strategies Targeting Diabetes-Associated Alzheimer's disease
DOI:
https://doi.org/10.48047/ef3qzv81Keywords:
Metabolic Dysfunction , Neurodegeneration, Diabetes, Alzheimer's diseaseAbstract
Background: Alzheimer’s disease represents a leading cause of dementia worldwide and is increasingly recognized as a complex,
multifactorial disorder extending beyond classical amyloid and tau pathologies. Growing epidemiological and mechanistic evidence highlights type 2 diabetes mellitus as a major risk factor for cognitive
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References
Biessels GJ, Despa F. Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications. Nat RevEndocrinol. 2018;14(10):591–604.
Chatterjee S, Peters SA, Woodward M, et al. Type 2 diabetes as a risk factor for dementia in women compared with men: a pooled analysis of 2.3 million people. Diabetes Care. 2016;39(2):300–307.
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