Minoxidil in the Management of Androgenetic Alopecia: Mechanisms of Action, Clinical Efficacy, and Emerging Formulations
DOI:
https://doi.org/10.48047/qgev7y30Keywords:
Minoxidil, Management, Androgenetic AlopeciaAbstract
Background: Androgenetic alopecia (AGA) is the most prevalent form of non-scarring hair loss and a chronic, progressive disorder
characterized by follicular miniaturization, shortened anagen duration, and patterned thinning in men and women. The condition carries a substantial psychosocial burden and often requires long-term therapy to preserve gains. Pathophysiologically, AGA reflects an interplay between genetic susceptibility and androgen signaling, particularly the effects of dihydrotestosterone on androgen-sensitive scalp follicles, with downstream dysregulation of dermal papilla function,
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References
Brzezińska-Wcisło L, Rakowska A, Rudnicka L, Bergler-Czop B, Czuwara J, Maj J. Androgenetic alopecia: diagnostic and therapeutic recommendations of the Polish Dermatological Society. Dermatol Rev. 2018;105(1):1–18.
Starace M, Orlando G, Alessandrini A, Piraccini BM. Female androgenetic alopecia: an update on diagnosis and management. Am J Clin Dermatol. 2020;21(1):69–84
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