Ultra-Hypofractionated Adjuvant Radiotherapy for Early Invasive Breast Cancer
DOI:
https://doi.org/10.48047/3040gm94Keywords:
Ultra-Hypofractionated, Adjuvant Radiotherapy ,Breast CancerAbstract
Background: Adjuvant radiotherapy following breast-conserving surgery is a cornerstone in the management of early invasive breast cancer,
significantly reducing local recurrence and improving long-term outcomes. Over the past two decades, fractionation schedules have evolved from conventional regimens to moderate hypofractionation, driven by radiobiological insights and robust clinical trial evidence. More recently, ultra-hypofractionated radiotherapy—typically delivered in five fractions over one week—has emerged as a novel paradigm, offering further treatment acceleration while maintaining oncologic efficacy
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References
Early Breast Cancer Trialists’ Collaborative Group (EBCTCG). Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials. Lancet. 2011;378(9804):1707-1716. doi:10.1016/S0140-6736(11)61629-2
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