Integrative Analysis of ANGPTL3 and APOB Gene Polymorphisms in Lipid Metabolism and Coronary Artery Disease Susceptibility

Authors

  • Randa H Mohamed, Tarek Ahmed Naguib, Rawda Omar Ali, Basma A. Ibrahim Author

DOI:

https://doi.org/10.48047/h18ps373

Keywords:

ANGPTL3, APOB Gene , Coronary Artery Disease

Abstract

Background: Coronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide, primarily driven by dyslipidemia and complex gene–environment interactions influencing lipid metabolism. The angiopoietin-like 3 (ANGPTL3) and apolipoprotein B (APOB) genes are central regulators of plasma lipid homeostasis and lipoprotein assembly, respectively. ANGPTL3 modulates lipoprotein lipase and endothelial lipase activity

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References

Benjamin EJ, Muntner P, Alonso A, et al. Heart disease and stroke statistics—2019 update: A report from the American Heart Association. Circulation. 2019;139(10):e56–e528.

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Published

2024-11-20

Issue

Vol. 53 No. 03 (2024): Year 2024, Volume 53, Issue 3

Section

Original

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How to Cite

Integrative Analysis of ANGPTL3 and APOB Gene Polymorphisms in Lipid Metabolism and Coronary Artery Disease Susceptibility (Randa H Mohamed, Tarek Ahmed Naguib, Rawda Omar Ali, Basma A. Ibrahim , Trans.). (2024). Cuestiones De Fisioterapia, 53(03), 6573-6581. https://doi.org/10.48047/h18ps373