Chondroprotective Effects of Avocado/Soybean Unsaponifiables Versus Glucosamine–Chondroitin Sulfate: A Comprehensive Review of Preclinical and Clinical Evidence

Authors

  • Ibrahim Ali Awwad , Elsayed Mohammed Kamel, Alaa Nasr Abdelwahab Mohamed, Zeinab Mahmoud Saeed Author

DOI:

https://doi.org/10.48047/gyex7084

Keywords:

Chondroprotective Effects, Glucosamine–Chondroitin Sulfate ,Comprehensive Review

Abstract

Osteoarthritis (OA) is the most prevalent degenerative joint disorder, characterized by progressive loss of articular cartilage, 
subchondral bone remodeling, synovial inflammation, and chronic pain. Conventional pharmacological options, including nonsteroidal antiinflammatory drugs (NSAIDs) and corticosteroids, primarily target symptoms but fail to halt or reverse cartilage degradation, often resulting  in adverse effects with long-term use

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References

Hunter DJ, Bierma-Zeinstra S. Osteoarthritis. Lancet. 2019;393(10182):1745-1759.

Bannuru RR, Osani MC, Vaysbrot EE, et al. OARSI guidelines for the non-surgical management of knee osteoarthritis. Osteoarthritis Cartilage. 2019;27(11):1578-1589.

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Published

2024-11-20

How to Cite

Chondroprotective Effects of Avocado/Soybean Unsaponifiables Versus Glucosamine–Chondroitin Sulfate: A Comprehensive Review of Preclinical and Clinical Evidence (Ibrahim Ali Awwad , Elsayed Mohammed Kamel, Alaa Nasr Abdelwahab Mohamed, Zeinab Mahmoud Saeed , Trans.). (2024). Cuestiones De Fisioterapia, 53(03), 6255-6271. https://doi.org/10.48047/gyex7084