Evaluation of Serum Factor H and Anti Factor H Antibodies in Children with Hemolytic Uremic Syndrome

Authors

  • Hany Elsayed Ibrahim, Mohamed Reda Abdelkader,Amal Saeed El Shal and Mohamed Ragab Abdellatif Author

DOI:

https://doi.org/10.48047/3jz67a83

Keywords:

Atypical hemolytic uremic syndrome; complement factor H; anti-factor H antibodies; children; thrombotic microangiopathy

Abstract

Atypical hemolytic uremic syndrome (aHUS) is a rare form of thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. Dysregulation of the alternative complement pathway, particularly involving complement factor H (CFH) deficiency or the presence of anti-factor H (anti-FH) antibodies

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References

Brocklebank V, Wood KM, Kavanagh D. Thrombotic microangiopathy and the kidney. Clin J Am Soc Nephrol. 2018;13(2):300-317. doi:10.2215/CJN.00620117

Hovinga JAK, Coppo P, Lämmle B, Moake JL, Miyata T, Vanhoorelbeke K. Thrombotic microangiopathies. Nat Rev Dis Primers. 2017;3:17020. doi:10.1038/nrdp.2017.20

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Published

2024-11-30

Issue

Vol. 53 No. 03 (2024): Year 2024, Volume 53, Issue 3

Section

Original

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How to Cite

Evaluation of Serum Factor H and Anti Factor H Antibodies in Children with Hemolytic Uremic Syndrome (Hany Elsayed Ibrahim, Mohamed Reda Abdelkader,Amal Saeed El Shal and Mohamed Ragab Abdellatif , Trans.). (2024). Cuestiones De Fisioterapia, 53(03), 5577-5587. https://doi.org/10.48047/3jz67a83