Pathogenesis and Emerging Therapeutic Lines in Behcet’s Disease: Integrating Genetic, Vascular, and Immunologic Insights with Clinical Translation
DOI:
https://doi.org/10.48047/y2xmm140Keywords:
Pathogenesis, Emerging Therapeutic, Immunologic Insights.Abstract
Behcet’s disease (BD) is a chronic, relapsing, multisystem vasculitis characterized by recurrent mucocutaneous, ocular, vascular, and neurological involvement. Its pathogenesis is complex and multifactorial, involving a combination of genetic susceptibility, environmental and microbial triggers, vascular-endothelial dysfunction, and dysregulation
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References
Davatchi F, Assaad-Khalil S, Calamia KT, et al. The International Criteria for Behçet’s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol. 2014;28(3):338-347.
Tugal-Tutkun I, Onal S, Altan-Yaycioglu R, Huseyin Altunbas H, Urgancioglu M. Uveitis in Behçet disease: an analysis of 880 patients. Am J Ophthalmol. 2004;138(3):373-380.
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