To determine the correlation of Triglyceride levels with HbA1c values in type 2 Diabetic patients

Authors

  • Dr S Moogaambiga Professor, Department of General Medicine, Vinayaka Mission’s Medical College and Hospitals, Vinayaka Mission’s Research Foundation (DU), Salem, Tamil Nadu, India Author
  • Dr S R RangaBashyam Professor, Department of General Medicine, Vinayaka Mission’s Medical College and Hospitals, Vinayaka Mission’s Research Foundation (DU), Salem, Tamil Nadu, India Author
  • Dr Nisha S Postgraduate, Department of General Medicine, Vinayaka Mission’s Medical College and Hospitals, Vinayaka Mission’s Research Foundation (DU), Salem, Tamil Nadu, India Author
  • Dr Vandana Sanjoy Mishra Postgraduate, Department of General Medicine, Vinayaka Mission’s Medical College and Hospitals, Vinayaka Mission’s Research Foundation (DU), Salem, Tamil Nadu, India Author

DOI:

https://doi.org/10.48047/7ngndg02

Abstract

Introduction: HbA1c could be used as a viable biomarker for predicting dyslipidemia and cardiovascular disease (CVD).Lipid abnormalities are common in diabetic population irrespective of insulin deficiency (or) resistance. The most common abnormality noted is hypertriglyceridemia.

Objectives: To determine the correlation of Triglyceride levels with HbA1c  values in Diabetic patients.

Materials and Methods: The study is an observational study. The sample size will be 100 patients for evaluation of triglyceride levels and HbA1c (by satisfying inclusion and exclusion criteria) after informed written consent. Triglyceride levels and HbA1c levels will be checked for the patients who are selected, and the statistical test will be done to determine the correlation between them.

Results: The participants were grouped into three categories based on HbA1c levels, participants with excellent control, good control and poor control. The mean and standard deviation of lipid parameters was higher in poorly controlled group. Positive correlation observed between triglyceride and HbA1c  (r=0.257).

Conclusion:Poorly controlled HbA1c has been found to be strongly linked to hypertriglyceridemia and also places them at high risk for cardiovascular disease. HbA1c levels can be used as an ideal marker for prediction of dyslipidemia. It can be used to screen high-risk diabetic patients for timely lipid-lowering medication intervention, averting unfavourable cardiovascular event

Downloads

Download data is not yet available.

References

K.Park. Park’s textbook of Preventive and Social Medicine. 26th ed. M/s Banarsidas Bhanot; 2021.

Firouzi S, BarakatunNizak MY, Nor Azmi et al. Nutritional status, glycemic control and its associated risk factors among a sample of type 2 diabetic individuals, a pilot study. J Res Med Sci2015;20:40–6.

International Diabetes Federation. India diabetes report 2000 — 2045 [Internet]. 2021 [cited 2022 Mar 14];Available from: https://www.diabetesatlas.org/data/

Kundu D, Saikia M, Paul T. Study of the Correlation between Total Lipid Profile and Glycosylated Hemoglobin Among the Indigenous Population of Guwahati. Int J Life SciSci Res 2019;3(4):567–72.

Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, et al. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition. Diabetes Res ClinPract2019;157:107843.

Alzahrani SH, Baig M, Aashi MM, Al-shaibi FK, Alqarni DA, Bakhamees WH. Association between glycated hemoglobin (HbA1c) and the lipid profile in patients with type 2 diabetes mellitus at a tertiary care hospital: a retrospective study. Diabetes MetabSyndrObes Targets Ther2019;12:1639–44.

Sabanayagam C, Liew G, Tai ES, Shankar A, Lim SC, Subramaniam T, et al. Relationship between glycated haemoglobin and microvascular complications: is there a natural cut-off point for the diagnosis of diabetes? Diabetologia 2009;52(7):1279–89.

Hirano T. Pathophysiology of Diabetic Dyslipidemia. J AtherosclerThromb 2018;25(9):771–82.

Saurabh S, Ghalaut P et al. (PDF) TITLE : Association between Glycosylated Haemoglobin and Serum Lipid Profile in Patients with Type 2 Diabetes Mellitus. IARCorsortium 2020;1(2):51–5.

Dshmukh S, Singh VB, Hb CK, Meena B, Beniwal S, Saini VK. Can Hba1c be a marker for cardiovascular risk in type 2 Diabetes Mellitus. Int J Med Res Rev 2015;3(4):419–23.

Banday MZ, Sameer AS, Nissar S. Pathophysiology of diabetes: An overview. Avicenna J Med 2020;10(4):174–88.

Gillett MJ. International Expert Committee Report on the Role of the A1C Assay in the Diagnosis of Diabetes. ClinBiochem Rev 2009;30(4):197–200.

Downloads

Published

2024-11-27

How to Cite

To determine the correlation of Triglyceride levels with HbA1c values in type 2 Diabetic patients (. S. Moogaambiga, . S. R. . RangaBashyam, N. . S, & V. . Sanjoy Mishra , Trans.). (2024). Cuestiones De Fisioterapia, 53(03), 1829-1843. https://doi.org/10.48047/7ngndg02