Persistent Pulmonary Hypertension in the Modern NICU: Integrating Evidence-Based Therapies into Practice

Authors

  • Amira Adel Mohamed Eladl Specialist Registrar of Neonatology, NICU Department, Dubai Hospital Author
  • Inas Hamid Mohamed Soliman Specialist Registrar of Neonatology, NICU Department, Dubai Hospital Author

DOI:

https://doi.org/10.48047/dw8zee98

Keywords:

Persistent Pulmonary Hypertension, Evidence-Based Therapies

Abstract

Persistent pulmonary hypertension of the newborn (PPHN) happens when the normal drop in pulmonary vascular resistance (PVR) after birth doesn't occur properly, leading to a failure in circulatory transition. In the womb, the fetus naturally exists in a state of high pulmonary pressure. Oxygenated blood is delivered via the placenta through the umbilical vein. 

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References

Kiserud, T. Physiology of the fetal circulation. Semin. Fetal Neonat. Med. 2005, 10, 493503. [Google Scholar] [CrossRef] [PubMed]

Lakshminrusimha, S.; Steinhorn, R.H. Pulmonary vascular biology during neonatal transition. Clin. Perinatol. 1999, 26, 601–619. [Google Scholar] [PubMed]

Nair, J.; Lakshminrusimha, S. Update on pphn: Mechanisms and treatment. Semin. Perinatol. 2014, 38, 78–91. [Google Scholar] [CrossRef] [PubMed]

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Published

2024-12-05

Issue

Vol. 53 No. 03 (2024): Year 2024, Volume 53, Issue 3

Section

Articles

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How to Cite

Persistent Pulmonary Hypertension in the Modern NICU: Integrating Evidence-Based Therapies into Practice (A. A. . Mohamed Eladl & I. H. Mohamed Soliman , Trans.). (2024). Cuestiones De Fisioterapia, 53(03), 4971-4989. https://doi.org/10.48047/dw8zee98