Formulation of Nanoparticles & Structural identification of 5-flurouacil for anti-cancer activity
DOI:
https://doi.org/10.48047/5p9p6346Keywords:
Chemotherapy drug, NanoparticlesAbstract
The objective of this study was to assess the effectiveness of 5-FU, a chemotherapy drug, in treating cancer. The drug was specifically targeted to the tumor cells using CAP nanoparticles with FA attached to them. A dispersion of 10-30 mg of FAC copolymer was created in 20 ml of acetone. A solution of 5- FU (30 mg) was dissolved in acetone and then slowly added to the prepared FAC
solution.
Downloads
References
Jones, D. (2007). Cancer nanotechnology: small, but heading for the big time. Nature Reviews Drug Discovery, 6(3), 174-175. doi:10.1038/nrd2285.
Mukerjee, A., & Vishwanatha, J.K.(2009). Formulation, characterization and evaluation of curcumin-loaded plga nanospheres for cancer therapy. Anticancer Research, 29(10), 3867-75.
Müller, K.C. (2001) Pharmaceutically relevant metabolites from lichens. Applied Microbiology and Biotechnology, 56(1-2), 9-16. doi:10.1007/s002530100684.
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
