Evaluation of Sildenafil Citrate Therapy in the Management of Fetal Growth Restriction
DOI:
https://doi.org/10.48047/rhw3w796Keywords:
Intrauterine growth restriction, sildenafil citrate, fetal growth, Doppler ultrasound, uteroplacental circulation.Abstract
Objective: The objective of this study was to evaluate the effectiveness of sildenafil citrate in the treatment of intrauterine growth restriction (IUGR). Methods: This research constituted a single-group, non-randomized clinical trial with 258 pregnant women diagnosed with intrauterine growth restriction (IUGR), aged 19 to 35 years, with a gestational age of 27 weeks or greater. Each subject was administered sildenafil citrate (20 mg) thrice day until the conclusion of pregnancy.
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References
• Abo-El Roose, A. A., & Ghoneim, H. M. (2020). Effects of sildenafil citrate on impedance to flow in the umbilical and fetal middle cerebral arteries in pregnancies at high risk for fetal growth restriction. The Egyptian Journal of Fertility of Sterility, 24(1), 21-28.
• ACOG (2013): Fetal growth restriction. In Maternal-fetal evidence based guidelines (pp. 436-455). CRC Press.
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