Systematic in silico analysis suggests a protective role for progesterone receptor in pancreatic adenocarcinoma

Authors

  • Gulbahar Boyuk Ozcan and Burcu Biterge Sut Author

DOI:

https://doi.org/10.48047/p62dxz97

Keywords:

Progesterone receptor, PGR, gene expression, pancreatic adenocarcinoma, PAAD, cancer.

Abstract

Pancreatic adenocarcinoma (PAAD) is a highly lethal cancer, which is characterized by its aggressiveness and late diagnosis.  Progesterone receptor (PGR) has been associated with various malignancies in literature but its role in PAAD remains poorly understood. In this study, we investigated the role of progesterone receptor in PAAD using in silico analyses. 

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References

Abe, M., Yamashita, J. and Ogawa, M. (2000) ‘Medroxyprogesterone acetate inhibits human pancreatic carcinoma cell growth by inducing apoptosis in association with Bcl-2 phosphorylation’, Cancer, 88(9), pp. 2000–2009. Available at: https://doi.org/10.1002/(SICI)10970142(20000501)88:9<2000::AID-CNCR4>3.0.CO;2-B.

Alrushaid, N. et al. (2023) ‘Progress and Perspectives in Colon Cancer Pathology, Diagnosis, and Treatments’, Diseases, 11(4), p. 148. Available at: https://doi.org/10.3390/diseases11040148.

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Published

2025-04-03

How to Cite

Gulbahar Boyuk Ozcan and Burcu Biterge Sut. (2025). Systematic in silico analysis suggests a protective role for progesterone receptor in pancreatic adenocarcinoma. Cuestiones De Fisioterapia, 54(5), 490-519. https://doi.org/10.48047/p62dxz97