Systematic in silico analysis suggests a protective role for progesterone receptor in pancreatic adenocarcinoma
DOI:
https://doi.org/10.48047/p62dxz97Keywords:
Progesterone receptor, PGR, gene expression, pancreatic adenocarcinoma, PAAD, cancer.Abstract
Pancreatic adenocarcinoma (PAAD) is a highly lethal cancer, which is characterized by its aggressiveness and late diagnosis. Progesterone receptor (PGR) has been associated with various malignancies in literature but its role in PAAD remains poorly understood. In this study, we investigated the role of progesterone receptor in PAAD using in silico analyses.
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References
Abe, M., Yamashita, J. and Ogawa, M. (2000) ‘Medroxyprogesterone acetate inhibits human pancreatic carcinoma cell growth by inducing apoptosis in association with Bcl-2 phosphorylation’, Cancer, 88(9), pp. 2000–2009. Available at: https://doi.org/10.1002/(SICI)10970142(20000501)88:9<2000::AID-CNCR4>3.0.CO;2-B.
Alrushaid, N. et al. (2023) ‘Progress and Perspectives in Colon Cancer Pathology, Diagnosis, and Treatments’, Diseases, 11(4), p. 148. Available at: https://doi.org/10.3390/diseases11040148.
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