FORMULATION DEVELOPMENT OF CURCUMIN (CURCUMA LONGA EXTRACT) BUCCAL DELIVERY SYSTEM (ORAL LIQUID SPRAY)
DOI:
https://doi.org/10.48047/w989fs85Keywords:
curcumin, oral bioavailability, anti-inflammatory, analgesic, antioxidant properties, liquid formulation.Abstract
Background: The formulation aims to increase curcumin's oral bioavailability from Curcuma longa's rhizome. Curcuma longa rhizome colouring agent has anti-inflammatory, analgesic, and antioxidant properties. To tackle this problem, we created a curcumin formulation standardized to 95% potency in an emulsion that can be sprayed directly into the mouth. Materials& Method: The materials under scrutiny are Turmeric extract containing 95% curcumin, Sorbitol solution (non-crystallizing) Sodium Benzoate, Polysorbate, Propylene Glycol, Glycerin, Acrysol K-140, Xanthan gum, Sucralose, Butylated Hydroxyanisole, Butylated Hydroxytoluene, Menthol crystals, Orange booster (IFF), Anhydrous citric acid, Distilled water.
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References
Kocaadam B, Şanlier N. Curcumin, an active component of turmeric (Curcuma longa), and its effects on health. Crit Rev Food Sci Nutr. 2017 Sep 2;57(13):28892895. doi: 10.1080/10408398.2015.1077195.
Hay E, Lucariello A, Contieri M, Esposito T, De Luca A, Guerra G, Perna A. Therapeutic effects of turmeric in several diseases: An overview. Chem Biol Interact. 2019 Sep 1;310:108729. doi: 10.1016/j.cbi.2019.108729.
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