5-HT and Neurotransmitter Modulation in obesity: A potential Therapeutic Target.
DOI:
https://doi.org/10.48047/6evb3n80Keywords:
Obesity, gut microbiota, pathogenesis of obesity, obesity and neuroinflammation, brain pathways to obesity, neurotransmission.Abstract
Today, obesity has become a global pandemic affecting billions of people worldwide. It is associated with increased risks of various diseases, including cardiovascular and musculoskeletal diseases, psychiatric disorders, cancer, and diabetes, making it a significant
public health issue. The escalating prevalence of obesity has led to a substantial number of deaths globally, with obesity rates rising significantly over the past forty years. In 2016, over 1.9 billion adults were overweight, and more than 650 million were obese, indicating that 39% of adults were overweight and 13% were obese. Obesity has also been linked to an elevated risk of metabolic diseases and changes in brain structure and function
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References
The Lancet Gastroenterology & Hepatology. Obesity: Another ongoing pandemic. Lancet Gastroenterol. Hepatol. 2021, 6, 411.
Luppino, F.S.; de Wit, L.M.; Bouvy, P.F.; Stijnen, T.; Cuijpers, P.; Penninx, B.W.J.H.; Zitman, F.G. Overweight, Obesity, andDepression: A Systematic Review and Meta-analysis of Longitudinal Studies. Arch. Gen. Psychiatry 2010, 67, 220–229.
M Ng, T Fleming, M Robinson et al., “Global, regional, andnational prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013,” Lancet (London, England), vol. 384, no. 9945, pp. 766–81, 2014.
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