In-vitro anti-inflammatory mechanism of Averrhoa carambola L. (Star Fruit) leaves on RAW 264.7 macrophage inflammation model induced by LPS.

Authors

  • Bhaskar Jyoti Pathak Research Scholar and Assistant Professor, Royal School of Pharmacy, The Assam Royal Global University, Betkuchi, Guwahati-781035 Author
  • Dr. Atanu Bhattacharjee Professor, Royal School of Pharmacy, The Assam Royal Global University, Betkuchi, Guwahati-781035 Author
  • Neelakshi Sharma Assistant Professor, Royal School of Pharmacy, The Assam Royal Global University, Betkuchi, Guwahati-781035 Author
  • Tanmay Sarma Assistant Professor, Royal School of Pharmacy, The Assam Royal Global University, Betkuchi, Guwahati-781035 Author
  • Kamal Deka Assistant Professor, Royal School of Pharmacy, The Assam Royal Global University, Betkuchi, Guwahati-781035 Author
  • Sumi Barman Assistant Professor, Royal School of Pharmacy, The Assam Royal Global University, Betkuchi, Guwahati-781035 Author
  • Hadiuz Zaman Assistant Professor, Amity Medical School, Amity University, Haryana Author
  • Shiny Ahmed Assistant Professor, Royal School of Pharmacy, The Assam Royal Global University, Betkuchi, Guwahati-781035 Author

DOI:

https://doi.org/10.48047/eqgaff49

Keywords:

Averrhoa carambola L., Inflammation, IL-1β, IL-6 and TNF-α.

Abstract

The leaves of Averrhoa carambola L. (Oxalidaceae) have traditionally been used in folk medicine for alleviating pain and inflammation. This study explored the anti-inflammatory properties of A. carambola leaf extracts. The extraction was performed using the Soxhlet method, starting with petroleum ether and subsequently using 95% ethanol. 

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References

Aggarwal, Bharat, et al. "TNF Blockade: An Inflammatory Issue." Cytokines as Potential Therapeutic Targets for Inflammatory Skin Diseases, edited by Numer of R, Dinarello DA, and Asadullah K, Ernst Schering Research Foundation Workshop, Springer, 2006, pp. 161–186.

Fujiwara, N., and K. Kobayashi. "Macrophages in Inflammation." Current Drug Targets - Inflammation & Allergy, vol. 4, 2005, pp. 281–286.

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Published

2025-02-20

Issue

Vol. 54 No. 4 (2025): Year 2025, Volume 54, Issue 4

Section

Articles

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How to Cite

Jyoti Pathak, B. ., Bhattacharjee, . A., Sharma, N. ., Sarma, T., Deka, K. ., Barman, S., Zaman, H., & Ahmed, S. . (2025). In-vitro anti-inflammatory mechanism of Averrhoa carambola L. (Star Fruit) leaves on RAW 264.7 macrophage inflammation model induced by LPS . Cuestiones De Fisioterapia, 54(4), 7233-7244. https://doi.org/10.48047/eqgaff49