Lipid nano-emulsion for the treatment for breast cancer
DOI:
https://doi.org/10.48047/1ezgyg80Keywords:
Lipid nano emulsion, Nanocarrier, Bioavailability, Chemotherapeutics.Abstract
LNEs are being extensively researched as drug carriers along with additional nanocarriers for better drug delivery, especially when used for chemotherapeutics. They have the potential to cure breast cancer and other types of tumours by binding to receptor domains where LDLP-receptors are overexpressed. LNEs are oil-water dispersions with the nanoscale droplets stabilised by a surface
active layer where they mitigate the creaming and sedimentation throughout storage and coalescence, resulting in an even greater oil-in-water vicinity
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References
Chen, L., et al., An optimized two-vial formulation lipid nanoemulsion of paclitaxel for targeted delivery to tumor. 2017. 534(1-2): p. 308-315.
Kalepu, S. and V. Nekkanti, Insoluble drug delivery strategies: review of recent advances and business prospects. Acta Pharm Sin B, 2015. 5(5): p. 442-53.
Tamilvanan, S., Oil-in-water lipid emulsions: implications for parenteral and ocular delivering systems. Progress in Lipid Research, 2004. 43(6): p. 489-533.
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