FORMULATION DEVELOPMENT, OPTIMIZATION, AND EVALUATION OF A SUSTAINED-RELEASE HYDROGEL SYSTEM OF EMPAGLIFLOZIN USING ALMOND AND NEEM GUMS
DOI:
https://doi.org/10.48047/w3v7en02Keywords:
Sustained-release hydrogel, Empagliflozin, Almond gum, Neem gum, FTIR analysis, Crosslinked hydrogels, Natural gum hydrogels,Abstract
The research proposes a sustained-release hydrogel formulation of Empagliflozin using natural polymers like almond gum and neem gum as biodegradable and biocompatible carriers. The drug delivery system aims to optimize the therapeutic efficacy in the management of Type 2 diabetes, and the hydrogel system controls the release of the drug for 24 hours, thereby improving patient compliance.
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References
Alwossabi A, Elamin ES, Ahmed EM, Abdelrahman M. Natural excipients applications in conventional pharmaceutical formulations-Part I. Med aromat plants(LosAngeles). 2021;10:397. 2. Amiri MS, Mohammadzadeh V, Yazdi ME, Barani M, Rahdar A, Kyzas GZ. Plant-based gums and mucilages applications in pharmacology and nanomedicine: a review. Molecules. 2021 Mar 22;26(6):1770.
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