CORRELATION OF LEPTIN AND ADIPONECTIN LEVELS WITH METABOLIC AND HORMONAL PROFILES IN PCOS PATIENTS: A COMPARATIVE STUDY WITH NORMAL CONTROLS
DOI:
https://doi.org/10.48047/0txjr632Keywords:
PCOS, leptin, adiponectin, insulin resistance, metabolic dysfunction, adiponectin-toleptin ratio, reproductive hormones.Abstract
Background: Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder characterized by metabolic and reproductive abnormalities, including insulin resistance and hyperandrogenism. Leptin and adiponectin, two adipokines involved in metabolic regulation, are known to be dysregulated in PCOS. This study aims to investigate the correlation between leptin and adiponectin levels and their association with metabolic and hormonal profiles in PCOS patients compared to healthy controls.
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References
Panidis, D., Koliakos, G., Kourtis, A., Katsikis, I., Krassas, G., & Koukoulis, G. (2003). Serum leptin levels are higher in non-obese women with polycystic ovary syndrome compared to those of age- and BMI-matched controls. European Journal of Endocrinology, 149(1), 25-29.
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