Effect of Bisphosphonates on Alveolar Bone Loss Around Osseointegrated Implants
DOI:
https://doi.org/10.48047/tazfyh73Keywords:
Bisphosphonates, Alveolar Bone Loss, Osseointegration, Dental Implants, Bone Remodeling, Implant DentistryAbstract
Background:
Alveolar bone stability is crucial for the long-term success of osseointegrated dental implants. Bisphosphonates,
which inhibit osteoclastic activity, have been proposed as an adjunctive therapy to mitigate bone resorption.
This study investigates the effect of bisphosphonate administration on alveolar bone loss surrounding dental
implants.
Materials and Methods:
In a prospective study, 40 patients requiring dental implants were randomly assigned into two groups. The
bisphosphonate group (n = 20) received oral alendronate at a dose of 70 mg per week for 6 months, while the
control group (n = 20) received standard implant care without bisphosphonate therapy. Standardized
radiographic evaluations were performed at baseline and after 6 months to measure changes in alveolar bone
levels.
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