Living Donner Liver Transplant in Hepatocellular Carcinoma
DOI:
https://doi.org/10.48047/vk452h51Keywords:
Liver Transplantation, Hepatocellular Carcinoma, Milan Criteria.Abstract
Liver transplantation for hepatocellular carcinoma (HCC) is the best treatment option for patients with early-stage tumours and accounts for ∼20–40% of all liver transplantations performed at most centres worldwide. The Milan criteria are the most common criteria to select patients with HCC for transplantation but they can be seen as too restrictive. Several proposals have been made
for a moderate expansion of the criteria, which result in good outcomes but with an increase in the risk of tumour recurrence. Novel surgical techniques have been developed to increase the available pool of organs for liver transplantation (such as living donor liver transplantation, donation after circulatory death and split livers), but the effect of these techniques on patients with HCC is still
under debate.
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References
E. De Martin, T. Berg, D. Samuel, M. Berenguer, P. Burra, C. Fondevila, J. K. Heimbach, G.-P. Pageaux, A. Sanchez-Fueyo and C. Toso(2024):EASL Clinical Practice Guidelines on liver transplantation.Journal of Hepatology,81(6),1040-1086. 2. T. E. STARZL, T. Marchioro, K. Von Kaulla, G. Hermann, R. Brittain and W. Waddell(1963):Homotransplantation of the liver in humans.Surgery, gynecology & obstetrics,117(659.
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