SITE-SPECIFIC DRUG DELIVERY BY USING MONOCLONAL ANTIBODIES: A REVIEW
DOI:
https://doi.org/10.48047/cps7qy20Keywords:
Off Target effect, Monoclonal Antibodies, Peptides, Conjugates,distractingAbstract
Drugs administered systemically can have off-target effects, which have made it difficult to design and develop novel therapies with the best possible efficacy and therapeutic index. In these regards, there are high hopes for the development of site-specific drug delivery solutions. Over the past three decades, a significant amount of effort has been put into comprehending and overcoming the biological barriers that prevent targeted drug delivery and distracting: developing techniques to remove such difficult barriers.
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References
Ehrlich, P., A general review of the recent work in immunity. In Collected Papers of Paul Ehrlich,
Vol. 2, Immunology and Cancer Research 1956, Pergamon Press, London, 1990, 442.
Larson, S.M., Brown, J.P., Wright, P.W., Carrasquillo, J.A., Hellstrom, I., and Hellstrom, K.E.,
Imaging of melanoma with I-labeled monoclonal antibodies, J. Nuclear Med., 24, 123–129, 1983.
Zurawski, V.R., Haber, E., and Black, P.H., Production of antibody to tetanus toxoid by continuous
human lymphoblastoid cell lines, Science, 199, 1439, 1978
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