Exploring the Antioxidant, Antidiabetic, and Anti-Inflammatory Properties of Cold Macerated Rumex nepalensis Leaf Extract: A Study on Its Role in Hyperglycaemia Control, Free Radical Scavenging, and the Development of a Nanogel for Therapeutic Use
DOI:
https://doi.org/10.48047/qjzfy738Keywords:
Rumex nepalensis, Antioxidant activity, Anti-inflammatory activity, Solid Lipid Nanoparticles, Antidiabetic properties, NanogelAbstract
The present study aimed to evaluate the phytochemical composition, antioxidant, antidiabetic, and antiinflammatory properties of methanolic leaf extract of Rumex nepalensis, codenamed RNME-L, along with the formulation and characterization of a nanogel incorporating solid lipid nanoparticles (SLNs). Preliminary phytochemical screening confirmed the presence of alkaloids, flavonoids, phenols, phytosterols, tannins, anthraquinones, and saponins, indicating potential pharmacological activities.
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References
Salleh NH, Zulkipli IN, Mohd Yasin H, Ja’afar F, Ahmad N, Wan Ahmad WAN, et al. Systematic review of medicinal plants used for treatment of diabetes in human clinical trials: An ASEAN perspective. Evidence-based complementary and alternative medicine. 2021;2021. [2] Shabab S, Gholamnezhad Z, Mahmoudabady M. Protective effects of medicinal plant against diabetes induced cardiac disorder: A review. Journal of ethnopharmacology. 2021;265:113328.
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