Formulation and Evaluation of Mucoadhesive buccal Film of Azilsartan Medoxomil By solvent casting method
DOI:
https://doi.org/10.48047/kn7sg737Keywords:
Buccalfilm, first-pass metabolism,solvent casting method, Azilsartan Medoxomil.Abstract
The drug azalisartan medoxomil is used to treat hypertension.The high first pass metabolism in the liver results in limited bioavailability. To increase patient compliance, therapeutic efficacy, and bioavailability, the current effort aims to develop
mucoadhesive buccal films of Azilsartan medoxomil. Using the solvent casting process, seven formulations of a mucoadhesive drug delivery system containing azilsartan medoxomil have been developed as buccal films for this study.
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References
Balaji, A., Krishnaveni, B. and Goud, V. Formulation and evaluation of mucoadhesive buccal films of atorvastatin using natural protein. Int J Pharm Pharm Sci. 2014; 6(2):332-337.
Dahiya, M., Saha, S. and Shahiwala, A.F. A review on mouth dissolving films. Current drug delivery. 2009; 6(5): 469-476.
Dargad, R.R., Parekh, J.D., Dargad, R.R. and Kukrety, S. Azilsartan: novel angiotensin receptor blocker. J Assoc Physicians India. 2016; 64(3): 96-98.
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