BIO ASSAY GUIDED FRACTIONATION AND STRUCTURAL DETERMINATION OF ISOLATED COMPOUNDS OF ERYCIBE PANICULATA ROXB.
DOI:
https://doi.org/10.48047/dczee835Keywords:
.Abstract
Pharmacological screening of plant preparations, followed by bioassay guided fractionation that isolates pure active plant ingredients, is one of the effective approaches for exploring traditional medicines as a source of novel medications. Hence, the aim of present study is to determine bioactive compound from LPE extracts of Erycibe paniculata Roxb. Elution of LPE extracts is done using column chromatography. We have gathered eight fractions designated from LPE-1 to LPE-8 and are tested against different bacterial strains. Out of all LPE-4 shown notable efficacy against tested bacteria. TLC is carried out for LPE-4 and the structural determination of active compound is done using spectral analysis (1HNMR). 1HNMR spectral analysis of LPE-4 fraction was identified as 23,4- dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one.
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References
Supriya, M., & Krishna, T. M. (2024). Phytochemical profiling and antibacterial activity of Erycibe paniculata Roxb. African Journal of Biomedical Research, 27(3), 283-292.
Swarnendu Mondal and Chowdhury Habibur Rahaman, Studies in pharmacognostic characters of the climber Erycibe paniculata Roxb. of Convolvulaceae, Journal of Medicinal Plants Studies 2020; 8(2): 112-125.
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